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List of works by Kenneth C. Anderson

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Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity.

scientific article published on 14 March 2010
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

scientific article
Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study

scientific article published on January 13, 2014
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma

scientific article published on April 2007
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

scientific article published on 28 April 2009
Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

scientific article
Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report

scientific article
Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells

scientific article published on 12 May 2009
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

scientific article
Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3.

scientific article published on 03 February 2011
Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.

scientific article published on 03 February 2011
Renal impairment in patients with multiple myeloma: a consensus statement on behalf of the International Myeloma Working Group

scientific article published on 18 October 2010
Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group

scientific article published on 21 March 2016
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications

scientific article
Antimyeloma activity of heat shock protein-90 inhibition.

scientific article published on 18 October 2005
Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans

scientific article published on January 15, 2013
Reversibility of symptomatic peripheral neuropathy with bortezomib in the phase III APEX trial in relapsed multiple myeloma: impact of a dose-modification guideline

scientific article
Bortezomib: proteasome inhibition as an effective anticancer therapy

scientific article
MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction

scientific article published on January 15, 2013
Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma

scientific article
Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application

scientific article
Pathogenesis of Myeloma

scientific article published on January 1, 2011
Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma

scientific article
Multiple myeloma

article
The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

scientific article published on 7 October 2004
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway

scientific article published on 25 September 2003
In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells

scientific article
A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia.

scientific article published on 8 July 2013
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

scientific article
Mechanism of Action of Proteasome Inhibitors and Deacetylase Inhibitors and the Biological Basis of Synergy in Multiple Myeloma

scientific article published on November 1, 2011
Prognostic significance of copy-number alterations in multiple myeloma

scientific article
Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.

scientific article published on 3 October 2012
Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy

scientific article published on 15 June 2009
Molecular sequelae of histone deacetylase inhibition in human malignant B cells

scientific article published on 16 January 2003
International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation

scientific article
Vorinostat or placebo in combination with bortezomib in patients with multiple myeloma (VANTAGE 088): a multicentre, randomised, double-blind study

scientific article
Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model

scientific article
International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation

scientific article published on 29 March 2011
Analysis of herpes zoster events among bortezomib-treated patients in the phase III APEX study

scientific article published on 18 August 2008
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma

scholarly article
Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

scientific article
Latest advances and current challenges in the treatment of multiple myeloma

scientific article published on February 21, 2012
Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment

scientific article published on July 2006
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

scholarly article
Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma

scientific article published on 15 May 2015
Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis

scientific article
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.

scientific article
Mobilization in myeloma revisited: IMWG consensus perspectives on stem cell collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimens

scientific article published on 26 June 2009
The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

scientific article
Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.

scholarly article

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