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Authors whose works are in public domain in at least one jurisdiction

List of works by Herbert W. Virgin

1-50 of 265 results

Autophagy in immunity and inflammation

scientific article

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

scientific article (publication date: 13 November 2008)

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

scientific article published on 18 January 2016

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

scientific article

Redefining chronic viral infection

scientific article

Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages

scientific article

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article published on 23 January 2018

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

scientific article

Complete sequence and genomic analysis of murine gammaherpesvirus 68

scientific article published on August 1, 1997

STAT1-dependent innate immunity to a Norwalk-like virus

scientific article

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

scientific article

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

scientific article

Herpesvirus latency confers symbiotic protection from bacterial infection

scientific article

Identification of a candidate therapeutic autophagy-inducing peptide

scientific journal article

Disease-specific alterations in the enteric virome in inflammatory bowel disease

scientific article

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

scientific journal article

Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens

scientific article

Murine norovirus: a model system to study norovirus biology and pathogenesis

scientific article

Autophagy genes in immunity

scientific article published on May 2009

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

scientific article

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

scientific article

The Virome in Mammalian Physiology and Disease

scientific article (publication date: 27 March 2014)

Autophagy links inflammasomes to atherosclerotic progression.

scientific article published on 20 March 2012

PKR-dependent autophagic degradation of herpes simplex virus type 1.

scientific article published on 15 January 2006

Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells

scientific article published on April 1999

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

scientific article published on 2 June 2015

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

scientific article published on May 2015

Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68.

scientific article

Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties.

scientific article

Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome

scientific article

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

scientific article

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

scientific article

The autophagy gene ATG5 plays an essential role in B lymphocyte development

scientific article published on 24 December 2007

Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle

scientific article published on January 2012

Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo

scientific article

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

scientific article

Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing)

scientific article

Autophagy proteins regulate the secretory component of osteoclastic bone resorption

scientific article published on 4 November 2011

Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence

scientific article

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

scientific article

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

scientific article published on 9 December 2015

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

scientific article

Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease.

scientific article published in December 1997

Autophagy is essential for effector CD8(+) T cell survival and memory formation

scientific article

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

scientific article published on August 2017

RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

retracted scholarly article

Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity

scientific article

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

scientific article

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma

scientific article

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells

scientific article