List of works - Dan Rujescu

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Large recurrent microdeletions associated with schizophrenia

scientific article

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

scientific article

Common variants conferring risk of schizophrenia

scientific article

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Identification of loci associated with schizophrenia by genome-wide association and follow-up

scientific article

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Common genetic variants influence human subcortical brain structures

scientific article

A genome-wide investigation of SNPs and CNVs in schizophrenia

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

Disruption of the neurexin 1 gene is associated with schizophrenia

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

scientific article

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

scientific article

Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections

scientific article

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

scientific article published on 03 May 2009

Neurexin 1 (NRXN1) deletions in schizophrenia

scientific article

Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

scientific article published on 30 October 2011

Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort

scientific journal article

Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

scientific article

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

scientific article

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

scientific article

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

scientific article published on 26 July 2011

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

scientific article

A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities

scientific article published on 19 January 2006

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

article

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

scientific article

Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia

scientific article published on March 2012

A comprehensive family-based replication study of schizophrenia genes

scientific article

Copy number variations in neurodevelopmental disorders

scientific article published on 17 July 2012

Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia

scientific article published on 28 September 2006

Higher glucose levels associated with lower memory and reduced hippocampal microstructure

scientific article

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

scientific article

Penetrance for copy number variants associated with schizophrenia

scientific article published on 29 June 2010

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls

scientific article

Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism

scientific article

Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression

scientific article published in February 2004

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease

scholarly article by Daniela C. Glatz et al published February 2006 in Journal of Neurochemistry

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease

scientific article

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

scientific article

Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans

scientific article published in January 2009

At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia

scientific article published on 16 March 2011

Factor structure and external validity of the PANSS revisited

scientific article

List of works by Dan Rujescu

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Large recurrent microdeletions associated with schizophrenia

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

Common variants conferring risk of schizophrenia

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Identification of loci associated with schizophrenia by genome-wide association and follow-up

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Identification of common variants associated with human hippocampal and intracranial volumes

Common genetic variants influence human subcortical brain structures

A genome-wide investigation of SNPs and CNVs in schizophrenia

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

Disruption of the neurexin 1 gene is associated with schizophrenia

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

Neurexin 1 (NRXN1) deletions in schizophrenia

Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort

Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia

A comprehensive family-based replication study of schizophrenia genes

Copy number variations in neurodevelopmental disorders

Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia

Higher glucose levels associated with lower memory and reduced hippocampal microstructure

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

Penetrance for copy number variants associated with schizophrenia

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls

Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism

Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans

At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia

Factor structure and external validity of the PANSS revisited