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List of works by Jaakko Tuomilehto

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Analysis of protein-coding genetic variation in 60,706 humans

scientific article (publication date: 17 August 2016)
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

scientific article (publication date: 3 May 2001)
Biological, clinical and population relevance of 95 loci for blood lipids

scientific article
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

scientific article (publication date: June 2007)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)
Genetic studies of body mass index yield new insights for obesity biology

scientific article
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men

scientific article published on 4 December 2002
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

scientific article (publication date: 29 May 2003)
Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article
Discovery and refinement of loci associated with lipid levels

scientific article
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article
Age-related clonal hematopoiesis associated with adverse outcomes

scientific article
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article
Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators

scientific article published in September 1997
Newly identified loci that influence lipid concentrations and risk of coronary artery disease

scientific article
Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article
Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article
Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States

scientific article published in May 2003
Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study

scientific article
Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article
Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)
ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collab

scientific article
Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

scientific article
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article
The diabetes risk score: a practical tool to predict type 2 diabetes risk

scientific article
A reference panel of 64,976 haplotypes for genotype imputation

scientific article
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease

scientific article
Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial

scientific article published in October 1998
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

scientific article published on 12 March 2015
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article
New genetic loci link adipose and insulin biology to body fat distribution

scientific article
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article
The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity

scientific article published in December 2003
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)

article published 13 June 2006 in European Heart Journal
Early growth and coronary heart disease in later life: longitudinal study

scientific article published in April 2001
Catch-up growth in childhood and death from coronary heart disease: longitudinal study

scientific article published on February 1999
Variants in MTNR1B influence fasting glucose levels

scientific article
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012
Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations

scientific article
High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men.

scientific article published on September 1992
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article
Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease

scientific article published in November 2005
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

scientific article
The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)
Worldwide increase in incidence of Type I diabetes--the analysis of the data on published incidence trends

scientific article
Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women

scientific article

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