List of works - Panos Deloukas

Initial sequencing and analysis of the human genome

scientific article published on 15 February 2001

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

A second generation human haplotype map of over 3.1 million SNPs

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Integrating common and rare genetic variation in diverse human populations

scientific article (publication date: 2 September 2010)

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Genome-wide detection and characterization of positive selection in human populations

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Signatures of mutation and selection in the cancer genome

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Relative impact of nucleotide and copy number variation on gene expression phenotypes

scientific article (publication date: 9 February 2007)

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Genomewide association analysis of coronary artery disease

scientific article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Common regulatory variation impacts gene expression in a cell type-dependent manner

scientific article (publication date: 4 September 2009)

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Population genomics of human gene expression

scientific article (publication date: October 2007)

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

scientific article (publication date: July 2007)

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

scientific article

Convergent adaptation of human lactase persistence in Africa and Europe

scientific article

The fine-scale structure of recombination rate variation in the human genome

scientific article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Multiple common variants for celiac disease influencing immune gene expression

scientific article

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

scientific article published on 29 September 2013

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Mapping cis- and trans-regulatory effects across multiple tissues in twins

scientific article published on 02 September 2012

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Genome-wide association analysis identifies 20 loci that influence adult height

scientific article (publication date: May 2008)

Human metabolic individuality in biomedical and pharmaceutical research

scientific article (publication date: 31 August 2011)

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

scientific article published on 24 September 2006

A Gene Map of the Human Genome

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

scientific article

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

scientific article

List of works by Panos Deloukas

Initial sequencing and analysis of the human genome

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

A second generation human haplotype map of over 3.1 million SNPs

Biological, clinical and population relevance of 95 loci for blood lipids

Integrating common and rare genetic variation in diverse human populations

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Genetic studies of body mass index yield new insights for obesity biology

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Genome-wide detection and characterization of positive selection in human populations

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Signatures of mutation and selection in the cancer genome

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Discovery and refinement of loci associated with lipid levels

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Relative impact of nucleotide and copy number variation on gene expression phenotypes

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Genomewide association analysis of coronary artery disease

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Common regulatory variation impacts gene expression in a cell type-dependent manner

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Population genomics of human gene expression

Defining the role of common variation in the genomic and biological architecture of adult human height

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Large-scale association analysis identifies new risk loci for coronary artery disease

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Genome-wide association study identifies eight loci associated with blood pressure

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Convergent adaptation of human lactase persistence in Africa and Europe

The fine-scale structure of recombination rate variation in the human genome

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Multiple common variants for celiac disease influencing immune gene expression

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Mapping cis- and trans-regulatory effects across multiple tissues in twins

New genetic loci link adipose and insulin biology to body fat distribution

Genome-wide association analysis identifies 20 loci that influence adult height

Human metabolic individuality in biomedical and pharmaceutical research

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

A Gene Map of the Human Genome

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies