List of works - Leena Peltonen-Palotie

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Integrating common and rare genetic variation in diverse human populations

scientific article (publication date: 2 September 2010)

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Large recurrent microdeletions associated with schizophrenia

scientific article

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Common variants conferring risk of schizophrenia

scientific article

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

scientific article

Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

scientific article

Multiple common variants for celiac disease influencing immune gene expression

scientific article

The Collaborative Cross, a community resource for the genetic analysis of complex traits

article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

scientific article

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Identification of a variant associated with adult-type hypolactasia

scientific article (publication date: February 2002)

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study

scientific article

Variants in MTNR1B influence fasting glucose levels

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

scientific article

Classical twin studies and beyond

scientific article

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

scientific article

Aire regulates negative selection of organ-specific T cells

scientific article (publication date: April 2003)

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Genome-wide association study identifies five loci associated with lung function

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

Identification of ten loci associated with height highlights new biological pathways in human growth

scientific article

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

scientific article

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

scientific article

Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory

scientific article published in November 2005

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

scientific article published on 10 January 2010

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

scientific article

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

scientific article published on 08 February 2009

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).

scientific article published on 29 February 2004

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

List of works by Leena Peltonen-Palotie

Biological, clinical and population relevance of 95 loci for blood lipids

Integrating common and rare genetic variation in diverse human populations

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Large recurrent microdeletions associated with schizophrenia

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Common variants conferring risk of schizophrenia

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Common variants at 30 loci contribute to polygenic dyslipidemia

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Multiple common variants for celiac disease influencing immune gene expression

The Collaborative Cross, a community resource for the genetic analysis of complex traits

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Identification of a variant associated with adult-type hypolactasia

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study

Variants in MTNR1B influence fasting glucose levels

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Classical twin studies and beyond

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

Aire regulates negative selection of organ-specific T cells

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

Genome-wide association study identifies five loci associated with lung function

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Identification of ten loci associated with height highlights new biological pathways in human growth

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways