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List of works by Elina Ikonen

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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

scientific article
Cellular cholesterol trafficking and compartmentalization

scientific article published on February 2008
The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015
BODIPY-cholesterol: a new tool to visualize sterol trafficking in living cells and organisms

scientific article published on 19 July 2008
Mechanisms for cellular cholesterol transport: defects and human disease

scientific article published on October 2006
Modulation of cellular cholesterol transport and homeostasis by Rab11.

scientific article
Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae

scientific article published on December 19, 2001
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

scientific article
Zebrafish: gaining popularity in lipid research

scientific article published on July 2010
Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease

scientific article published in April 2002
Seipin regulates ER-lipid droplet contacts and cargo delivery.

scientific article
PNPLA3 mediates hepatocyte triacylglycerol remodeling

scientific article
Significance of sterol structural specificity. Desmosterol cannot replace cholesterol in lipid rafts

scientific article
Cellular pathology of Niemann-Pick type C disease

scientific article published on August 2004
Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease

scientific article published in February 2003
Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells

scientific article
Role of ORPs in sterol transport from plasma membrane to ER and lipid droplets in mammalian cells.

scientific article published on 6 December 2010
Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures

scientific article
Desmosterol and DHCR24: unexpected new directions for a terminal step in cholesterol synthesis.

scientific article published on 02 October 2013
Respiratory disease in Niemann-Pick type C2 is caused by pulmonary alveolar proteinosis

scientific article published on 10 December 2009
Sterol binding by OSBP-related protein 1L regulates late endosome motility and function

scientific article published on 6 August 2010
When intracellular logistics fails--genetic defects in membrane trafficking.

scientific article published on December 2006
Endocytic trafficking of sphingomyelin depends on its acyl chain length

scientific article
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes

scientific article published on 13 January 2007
LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route.

scientific article
Overexpression of OSBP-related protein 2 (ORP2) induces changes in cellular cholesterol metabolism and enhances endocytosis.

scientific article
MLN64 is involved in actin-mediated dynamics of late endocytic organelles

scientific article
NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation.

scientific article published on 26 June 2013
Lipid microdomains and insulin resistance: is there a connection?

scientific article
Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes

scientific article
Role for LAMP-2 in endosomal cholesterol transport

scientific article published on February 2011
Macrophage cholesterol transport: a critical player in foam cell formation

scientific article
Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

scientific article published on 13 September 2018
Secretion of sterols and the NPC2 protein from primary astrocytes

scientific article published on 7 September 2004
Synthesis and biosynthetic trafficking of membrane lipids.

scientific article published on August 2011
Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction.

scientific article published on 23 June 2007
LAPTM4B facilitates late endosomal ceramide export to control cell death pathways.

scientific article published on 17 August 2015
FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages.

scientific article
Differential mobilization of newly synthesized cholesterol and biosynthetic sterol precursors from cells

scientific article published on 25 March 2003
D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage

scientific article
Elevated levels of StAR-related lipid transfer protein 3 alter cholesterol balance and adhesiveness of breast cancer cells: potential mechanisms contributing to progression of HER2-positive breast cancers

scientific article published on 12 February 2015
ORP2, a homolog of oxysterol binding protein, regulates cellular cholesterol metabolism

scientific article
Alleviation of seipinopathy-related ER stress by triglyceride storage.

scientific article published on 18 December 2012
LDL-cholesterol transport to the endoplasmic reticulum: current concepts.

scientific article published on 6 April 2016
Cholesterol substitution increases the structural heterogeneity of caveolae.

scientific article
Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain

scientific article published on 20 October 2009
Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages

scientific article published on 19 March 2009
Association of tamoxifen resistance and lipid reprogramming in breast cancer

scientific article published on 24 August 2018
Cln5-deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism

scientific article
What dictates the accumulation of desmosterol in the developing brain?

scientific article published on 10 December 2012

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