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Authors whose works are in public domain in at least one jurisdiction

List of works by Hao Wu

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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death

scientific article published in Science
Structures and gating mechanism of human TRPM2

scientific article
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

scientific article published on 01 May 2019
DNA melting initiates the RAG catalytic pathway

scientific article published on 30 July 2018
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

scientific article published on 04 May 2020
Gasdermin D activity in inflammation and host defense

scientific article published on 01 September 2019
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing

scientific article published on 08 January 2020
Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

scientific article published on 14 April 2020
DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation

scientific article published on 17 March 2021
Michael G. Rossmann (1930-2019)

scientific article published on 01 August 2019
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

scientific article published on 01 September 2020
Could AlphaFold revolutionize chemical therapeutics?

scientific article published on 24 September 2021
Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway

Structural basis of γ chain family receptor sharing at the membrane level

scientific article published on 03 August 2023
Gasdermin D pore structure reveals preferential release of mature interleukin-1

scientific article published on 21 April 2021
Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4)

scientific article published on 24 January 2019
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175

scientific article published on 25 March 2022
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

scientific article published on 06 April 2022
BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL

scientific article published in 2022

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