List of works - Stefan Senger

A critical assessment of docking programs and scoring functions

scientific article (publication date: 5 October 2006)

Scientific competency questions as the basis for semantically enriched open pharmacological space development

scientific article

The application of the open pharmacological concepts triple store (Open PHACTS) to support drug discovery research

scientific article published in 2014

Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects

scientific article

Structure- and property-based design of factor Xa inhibitors: Pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs

article

Arylsulfonamides: A study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors

scientific article published in 2006

Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor

scientific article published on 8 June 2010

Selective and dual action orally active inhibitors of thrombin and factor Xa

scientific article

Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor

scientific article published on 14 July 2010

Zeolites as Transition-Metal-Free Hydrogenation Catalysts: A Theoretical Mechanistic Study

scientific article published in 2000

Open Data For Drug Discovery: Learning From The Biological Community

scientific article published on October 1, 2012

Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor

scientific article published on 30 March 2010

Sulfonamide-related conformational effects and their importance in structure-based design

scientific article

Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors

article

Using Tversky similarity searches for core hopping: finding the needles in the haystack

scientific article published in June 2009

Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides

scientific article

Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform

Managing expectations: assessment of chemistry databases generated by automated extraction of chemical structures from patents

scientific article (publication date: December 2015)

Toward a Low-Barrier Transition-Metal-Free Catalysis of Hydrogenation Reactions: A Theoretical Mechanistic Study of HAlX4-Catalyzed Hydrogenations of Ethene (X = F, Cl, and Br)

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs

scientific article

Compression of molecular interaction fields using wavelet thumbnails: application to molecular alignment

scientific article published on 27 February 2012

Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs

scientific article

BRADSHAW: a system for automated molecular design

scientific article published on 21 October 2019

Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform

The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs

scientific article

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs

scientific article

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs

scientific article

Assessment of the significance of patent-derived information for the early identification of compound–target interaction hypotheses

scientific article published on April 21, 2017

Correction to: BRADSHAW: a system for automated molecular design

scientific article published on 06 November 2019

Wavelet Approximation of GRID Fields: Application to Quantitative Structure-Activity Relationships

scientific article published on 23 September 2010

The quest for Factor VIIa exosite inhibitors

scientific article published in 2007

SAR Knowledge Bases in Drug Discovery

2-Vinylmethylenecyclopropane/3-Methylenecyclopentene Rearrangement: Matrix-Infrared Spectroscopic Identification of 4-Methylene-2-pentene-1,5-diyl (1,2‘-Bisallyl Diradical)

scientific article published in 1997

Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery

scientific article (publication date: 2013)

List of works by Stefan Senger

A critical assessment of docking programs and scoring functions

Scientific competency questions as the basis for semantically enriched open pharmacological space development

The application of the open pharmacological concepts triple store (Open PHACTS) to support drug discovery research

Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects

Structure- and property-based design of factor Xa inhibitors: Pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs

Arylsulfonamides: A study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors

Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor

Selective and dual action orally active inhibitors of thrombin and factor Xa

Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor

Zeolites as Transition-Metal-Free Hydrogenation Catalysts: A Theoretical Mechanistic Study

Open Data For Drug Discovery: Learning From The Biological Community

Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor

Sulfonamide-related conformational effects and their importance in structure-based design

Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors

Using Tversky similarity searches for core hopping: finding the needles in the haystack

Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides

Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform

Managing expectations: assessment of chemistry databases generated by automated extraction of chemical structures from patents

Toward a Low-Barrier Transition-Metal-Free Catalysis of Hydrogenation Reactions: A Theoretical Mechanistic Study of HAlX4-Catalyzed Hydrogenations of Ethene (X = F, Cl, and Br)

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs

Compression of molecular interaction fields using wavelet thumbnails: application to molecular alignment

Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs

BRADSHAW: a system for automated molecular design

Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform

The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs

Assessment of the significance of patent-derived information for the early identification of compound–target interaction hypotheses

Correction to: BRADSHAW: a system for automated molecular design

Wavelet Approximation of GRID Fields: Application to Quantitative Structure-Activity Relationships

The quest for Factor VIIa exosite inhibitors

SAR Knowledge Bases in Drug Discovery

2-Vinylmethylenecyclopropane/3-Methylenecyclopentene Rearrangement: Matrix-Infrared Spectroscopic Identification of 4-Methylene-2-pentene-1,5-diyl (1,2‘-Bisallyl Diradical)

Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery