List of works - Daniel Geschwind

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

scientific article

Strong association of de novo copy number mutations with autism

scientific article

Functional impact of global rare copy number variation in autism spectrum disorders

scientific article published on 15 July 2010

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Cancerous stem cells can arise from pediatric brain tumors

scientific article

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

scientific article (publication date: 25 May 2011)

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

An anatomically comprehensive atlas of the adult human brain transcriptome

scientific article (publication date: 20 September 2012)

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

scientific article

Advances in autism genetics: on the threshold of a new neurobiology

scientific article

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

scientific article (publication date: June 2011)

Common genetic variants on 5p14.1 associate with autism spectrum disorders

scientific article

Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene

scientific article

Functional organization of the transcriptome in human brain

scientific article published on 12 October 2008

Transcriptional landscape of the prenatal human brain

scientific article

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

scientific article

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

scientific article

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism

scientific article published on November 2013

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

scientific article

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

scientific article

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

scientific article published on 25 May 2015

A genome-wide scan for common alleles affecting risk for autism

scientific journal article

Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders

scientific article

A functional genetic link between distinct developmental language disorders

scientific article

Conservation and evolution of gene coexpression networks in human and chimpanzee brains

scholarly article

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

scientific article published on November 27, 2011

Sex differences in autism spectrum disorders

scientific article

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

scientific article published in May 2002

FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains

scientific article published on 19 February 2006

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

scientific article

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

scientific article

Genetics of autism spectrum disorders

scientific article published on 18 August 2011

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis

scientific article

Advancing the understanding of autism disease mechanisms through genetics

scientific article

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

scientific article published on 26 February 2018

Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Common genetic variants, acting additively, are a major source of risk for autism

scientific article

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

scientific article published on January 28, 2014

Advances in autism

scientific article

A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging

scientific article

Cortical Evolution: Judge the Brain by Its Cover

scientific article published on October 30, 2013

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

scientific article

Gene hunting in autism spectrum disorder: on the path to precision medicine

scientific article published on April 16, 2015

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

scientific article

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

scholarly article

The Central Nervous System and the Gut Microbiome.

scientific article

Early asymmetry of gene transcription in embryonic human left and right cerebral cortex

scientific article

List of works by Daniel Geschwind

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

Strong association of de novo copy number mutations with autism

Functional impact of global rare copy number variation in autism spectrum disorders

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Cancerous stem cells can arise from pediatric brain tumors

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

An anatomically comprehensive atlas of the adult human brain transcriptome

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

Advances in autism genetics: on the threshold of a new neurobiology

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

Common genetic variants on 5p14.1 associate with autism spectrum disorders

Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene

Functional organization of the transcriptome in human brain

Transcriptional landscape of the prenatal human brain

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

A genome-wide scan for common alleles affecting risk for autism

Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders

A functional genetic link between distinct developmental language disorders

Conservation and evolution of gene coexpression networks in human and chimpanzee brains

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

Sex differences in autism spectrum disorders

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

Genetics of autism spectrum disorders

Analysis of shared heritability in common disorders of the brain

Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis

Advancing the understanding of autism disease mechanisms through genetics

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Common genetic variants, acting additively, are a major source of risk for autism

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

Advances in autism

A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging

Cortical Evolution: Judge the Brain by Its Cover

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

Gene hunting in autism spectrum disorder: on the path to precision medicine

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

The Central Nervous System and the Gut Microbiome.

Early asymmetry of gene transcription in embryonic human left and right cerebral cortex