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Authors whose works are in public domain in at least one jurisdiction

List of works by Peter Keightley

1-50 of 93 results

Evolution of genes and genomes on the Drosophila phylogeny

scientific article

The distribution of fitness effects of new mutations

scientific article

MULTIFACTORIAL GENETICSUNDERSTANDING QUANTITATIVE GENETIC VARIATION

scientific article

Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila

scientific article

Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change

scientific article published on 17 June 2009

Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines

scientific article published on 13 May 2009

Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies

scientific article published on December 2007

Interference among deleterious mutations favours sex and recombination in finite populations

scientific article

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

scientific article

Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster

scientific article

Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison

scientific article

Evidence for widespread degradation of gene control regions in hominid genomes

scientific article

Quantifying the Slightly Deleterious Mutation Model of Molecular Evolution

article

Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila.

scientific article

Rates and Fitness Consequences of New Mutations in Humans

scientific article published on February 1, 2012

Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes.

scientific article published in January 2010

Evidence for pervasive adaptive protein evolution in wild mice

scientific article

Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents

scientific article

Current hypotheses for the evolution of sex and recombination

scientific article published on June 1, 2012

Toward a realistic model of mutations affecting fitness

scientific article published on March 1, 2003

Intron size and exon evolution in Drosophila

scientific article

Estimation of the spontaneous mutation rate per nucleotide site in a Drosophila melanogaster full-sib family.

scientific article

Contributions of protein-coding and regulatory change to adaptive molecular evolution in murid rodents

scientific article

Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii

scientific article published on 10 October 2012

Estimation of the spontaneous mutation rate in Heliconius melpomene

scientific article

The scale of mutational variation in the murid genome

scientific article published on 15 July 2005

The effect of variation in the effective population size on the rate of adaptive molecular evolution in eukaryotes.

scientific article

A method for inferring the rate of occurrence and fitness effects of advantageous mutations

scientific article published on 27 September 2011

A comparison of models to infer the distribution of fitness effects of new mutations

scientific article

What can we learn about the distribution of fitness effects of new mutations from DNA sequence data?

scientific article

Genomic selective constraints in murid noncoding DNA

scientific article

Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii

scientific article published on August 10, 2015

MCALIGN: stochastic alignment of noncoding DNA sequences based on an evolutionary model of sequence evolution

scientific article published on March 2004

Evolutionary constraints in conserved nongenic sequences of mammals.

scientific article published on October 2005

Spontaneous mutational variation for body size in Caenorhabditis elegans

scientific article

Faster-X adaptive protein evolution in house mice.

scientific article published on 20 December 2013

Regulatory variation at glypican-3 underlies a major growth QTL in mice

scientific article

Inference of Site Frequency Spectra From High-Throughput Sequence Data: Quantification of Selection on Nonsynonymous and Synonymous Sites in Humans

scientific article published on May 19, 2011

Global population divergence and admixture of the brown rat (Rattus norvegicus).

scientific article published in the Proceedings of the Royal Society B in October 2016

Analysis and implications of mutational variation.

scientific article published on 29 July 2008

PAPPA2, an enzyme that cleaves an insulin-like growth-factor-binding protein, is a candidate gene for a quantitative trait locus affecting body size in mice

scientific article

Genetic complexity of an obesity QTL ( Fob3) revealed by detailed genetic mapping

scientific article published on 01 June 2004

Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways

scientific article published on 14 December 2004

Estimating the rate of adaptive molecular evolution when the evolutionary divergence between species is small

scientific article

The role of advantageous mutations in enhancing the evolution of a recombination modifier

scientific article published on 5 February 2010

A resolution of the mutation load paradox in humans

scientific article

Positive and negative selection on noncoding DNA close to protein-coding genes in wild house mice.

scientific article published on 8 November 2010

The Nature of Genetic Variation for Complex Traits Revealed by GWAS and Regional Heritability Mapping Analyses

scientific article published on 19 October 2015

Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii

scientific article published on July 9, 2014

Fine mapping of a murine growth locus to a 1.4-cM region and resolution of linked QTL

scientific article published on 01 June 2004