List of works - Kie-Kian Ang

Human papillomavirus and survival of patients with oropharyngeal cancer.

scientific article

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

scientific article (publication date: 9 February 2006)

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

scientific article

Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

article

A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9

article

Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

scientific article published on 16 June 2008

Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis

scientific article published on September 2006

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

scientific article published on 22 October 2012

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

scientific article published in December 2002

Laryngeal cancer in the United States: changes in demographics, patterns of care, and survival.

scientific article published on September 2006

Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225

scientific article published on 29 June 2009

Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation.

scientific article

Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522.

scientific article

Validation of an accelerated 'demons' algorithm for deformable image registration in radiation therapy

scientific article published in June 2005

Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system

scientific article published in July 2004

Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer

scientific article published on May 7, 2012

CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines.

scientific article

American Society of Clinical Oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer

scientific article published on 10 July 2006

Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer

scientific article published on 01 November 2001

Evaluation of the dose for postoperative radiation therapy of head and neck cancer: First report of a prospective randomized trial

article

National Cancer Database report on cancer of the head and neck: 10-Year update

scientific article published on 01 June 2009

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

scientific article

Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma

scientific article

TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.

scientific article

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

scientific article published on 9 December 2014

Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck

scientific article

Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.

scientific article published on 31 October 2013

The epidermal growth factor receptor mediates radioresistance

scientific article published in September 2003

Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity

scientific article

Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial.

scientific article published on 15 December 2011

Multi-institutional trial of accelerated hypofractionated intensity-modulated radiation therapy for early-stage oropharyngeal cancer (RTOG 00-22).

scientific article

Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab

scientific article published in June 2007

Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003

scientific article published on 01 December 2004

The influence of positive margins and nerve invasion in adenoid cystic carcinoma of the head and neck treated with surgery and radiation

scientific article published on 01 June 1995

Accelerated fractionation in the radiation treatment of head and neck cancer. A critical comparison of different strategies

scientific article published on January 1988

Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of local and regional control

scientific article

Human Papillomavirus as a Marker of the Natural History and Response to Therapy of Head and Neck Squamous Cell Carcinoma

scientific article published on April 1, 2012

Final report of RTOG 9610, a multi-institutional trial of reirradiation and chemotherapy for unresectable recurrent squamous cell carcinoma of the head and neck

scientific article published on 01 March 2008

The epidemic of HPV-associated oropharyngeal cancer is here: is it time to change our treatment paradigms?

scientific article published on June 2011

Phase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Protocol 9911

scientific article published on 01 October 2007

Prospective risk-adjusted [18F]Fluorodeoxyglucose positron emission tomography and computed tomography assessment of radiation response in head and neck cancer

scientific article published on 30 March 2009

Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines

scientific article

Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies

scientific article published on 01 November 1993

Candidate dosimetric predictors of long-term swallowing dysfunction after oropharyngeal intensity-modulated radiotherapy

scientific article

Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients

scientific article published on 01 December 1993

Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy

scientific article published on 25 August 2008

miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13.

scientific article

miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue

scientific article published on May 2009

IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes.

scientific article published on 14 June 2008

Postoperative radiotherapy for malignant tumors of the parotid gland

scientific article published in January 1997

List of works by Kie-Kian Ang

Human papillomavirus and survival of patients with oropharyngeal cancer.

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

A radiation therapy oncology group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9

Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

Laryngeal cancer in the United States: changes in demographics, patterns of care, and survival.

Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225

Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation.

Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522.

Validation of an accelerated 'demons' algorithm for deformable image registration in radiation therapy

Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system

Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer

CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines.

American Society of Clinical Oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer

Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer

Evaluation of the dose for postoperative radiation therapy of head and neck cancer: First report of a prospective randomized trial

National Cancer Database report on cancer of the head and neck: 10-Year update

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma

TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck

Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.

The epidermal growth factor receptor mediates radioresistance

Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity

Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial.

Multi-institutional trial of accelerated hypofractionated intensity-modulated radiation therapy for early-stage oropharyngeal cancer (RTOG 00-22).

Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab

Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003

The influence of positive margins and nerve invasion in adenoid cystic carcinoma of the head and neck treated with surgery and radiation

Accelerated fractionation in the radiation treatment of head and neck cancer. A critical comparison of different strategies

Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of local and regional control

Human Papillomavirus as a Marker of the Natural History and Response to Therapy of Head and Neck Squamous Cell Carcinoma

Final report of RTOG 9610, a multi-institutional trial of reirradiation and chemotherapy for unresectable recurrent squamous cell carcinoma of the head and neck

The epidemic of HPV-associated oropharyngeal cancer is here: is it time to change our treatment paradigms?

Phase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Protocol 9911

Prospective risk-adjusted [18F]Fluorodeoxyglucose positron emission tomography and computed tomography assessment of radiation response in head and neck cancer

Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines

Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies

Candidate dosimetric predictors of long-term swallowing dysfunction after oropharyngeal intensity-modulated radiotherapy

Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients

Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy

miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13.

miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue

IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes.

Postoperative radiotherapy for malignant tumors of the parotid gland