List of works - Derek P. Jewell

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

scientific article

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

scientific article (publication date: July 2007)

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

scientific article (publication date: 2010)

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998.

scientific article published in February 2000

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

scientific article

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

scientific article

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review

scientific article

Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12

scientific article published on 01 October 1996

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

scientific article published on 27 April 2008

The molecular classification of the clinical manifestations of Crohn's disease

scientific article published on April 2002

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

scientific article

In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope.

scientific article

Predicting outcome in severe ulcerative colitis

scientific article

Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease

scientific article published on June 1989

Intensive intravenous regimen for severe attacks of ulcerative colitis

scientific article

Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres

scientific article

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

scientific article published in May 2005

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

article

Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease

scientific article

Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease.

scientific article published on May 1996

A comparison of budesonide with prednisolone for active Crohn's disease

scientific article published on 01 September 1994

Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history

scientific article published on March 1, 1998

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

scientific article (publication date: 15 May 2002)

Intestinal lymphocyte subpopulations in inflammatory bowel disease: an analysis by immunohistological and cell isolation techniques

scientific article

Azathioprine in ulcerative colitis: final report on controlled therapeutic trial

scientific article published in December 1974

Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.

scientific article published in August 2000

A comparison of budesonide and mesalamine for active Crohn's disease. International Budesonide-Mesalamine Study Group.

scientific article

Coeliac disease in primary care: case finding study

scientific article published on January 1999

Expression of HLA-DR antigens by colonic epithelium in inflammatory bowel disease

scientific article published on 01 September 1983

Clinical patterns of familial inflammatory bowel disease

scientific article

Genetic markers may predict disease behavior in patients with ulcerative colitis

scientific article

NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population

scientific article

Lymphocyte subset reference ranges in adult caucasians

scientific article published on August 1, 1991

Food intolerance and the irritable bowel syndrome

scientific article

Cytokine (TNF alpha, LT alpha and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies

scientific article published in February 2000

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

scientific article published on 21 December 2012

Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis

scientific article

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

scientific article

Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes

scientific article

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

scientific article

Circulating immune complexes in inflammatory bowel disease

scientific article published on 01 June 1973

Clinical relevance of advances in genetics and pharmacogenetics of IBD.

scientific article published on May 2004

The Lactulose Hydrogen Breath Test as a Diagnostic Test for Small-Bowel Bacterial Overgrowth

scientific article published on January 1, 1979

Role of the faecal stream in the maintenance of Crohn's colitis

scientific article

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

scientific article published in September 2013

Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine

scientific article

List of works by Derek P. Jewell

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998.

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

Common variants at five new loci associated with early-onset inflammatory bowel disease

The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review

Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

The molecular classification of the clinical manifestations of Crohn's disease

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope.

Predicting outcome in severe ulcerative colitis

Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease

Intensive intravenous regimen for severe attacks of ulcerative colitis

Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease

Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease.

A comparison of budesonide with prednisolone for active Crohn's disease

Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

Intestinal lymphocyte subpopulations in inflammatory bowel disease: an analysis by immunohistological and cell isolation techniques

Azathioprine in ulcerative colitis: final report on controlled therapeutic trial

Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.

A comparison of budesonide and mesalamine for active Crohn's disease. International Budesonide-Mesalamine Study Group.

Coeliac disease in primary care: case finding study

Expression of HLA-DR antigens by colonic epithelium in inflammatory bowel disease

Clinical patterns of familial inflammatory bowel disease

Genetic markers may predict disease behavior in patients with ulcerative colitis

NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population

Lymphocyte subset reference ranges in adult caucasians

Food intolerance and the irritable bowel syndrome

Cytokine (TNF alpha, LT alpha and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

Circulating immune complexes in inflammatory bowel disease

Clinical relevance of advances in genetics and pharmacogenetics of IBD.

The Lactulose Hydrogen Breath Test as a Diagnostic Test for Small-Bowel Bacterial Overgrowth

Role of the faecal stream in the maintenance of Crohn's colitis

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine