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List of works by Jacques Epelbaum

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article
Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

scientific article
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019
Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women

scientific article
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature

scientific article
Somatostatinergic systems in brain: networks and functions

scientific article published on 22 September 2007
Ultradian Rhythmicity of Ghrelin Secretion in Relation with GH, Feeding Behavior, and Sleep-Wake Patterns in Rats

article published in 2002
Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis

article
Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats

scientific article
Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents

scientific article
Somatostatin, Alzheimer's disease and cognition: an old story coming of age?

scientific article published on 10 July 2009
Ghrelin and Obestatin Circadian Levels Differentiate Bingeing-Purging from Restrictive Anorexia Nervosa

scientific article published on March 25, 2010
The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

scientific article
Systematic Analysis of Candidate Genes for Alzheimer's Disease in a French, Genome-Wide Association Study

article
Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset

scientific article published on 2 January 2007
Effects of Chronic Calorie Restriction or Dietary Resveratrol Supplementation on Insulin Sensitivity Markers in a Primate, Microcebus murinus

scientific article published on March 30, 2012
Medial septal GABAergic neurons express the somatostatin sst2A receptor: functional consequences on unit firing and hippocampal theta.

scientific article
Cellular localization of apelin and its receptor in the anterior pituitary: evidence for a direct stimulatory action of apelin on ACTH release

scientific journal article
Insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Alzheimer's disease.

scientific article published on 26 September 2012
Novel analogs of ghrelin: physiological and clinical implications

scientific article published on 01 August 2004
Somatostatin contributes to in vivo gamma oscillation modulation and odor discrimination in the olfactory bulb.

scientific article published in January 2010
Caloric restriction or resveratrol supplementation and ageing in a non-human primate: first-year outcome of the RESTRIKAL study in Microcebus murinus

scientific article
Ghrelin/obestatin ratio in two populations with low bodyweight: constitutional thinness and anorexia nervosa.

scientific article
Characterisation of [125I]-Tyr0DTrp8-somatostatin binding in sst1- to sst4- and SRIF-gene-invalidated mouse brain

scientific article published on 21 May 2003
Targeting sst2A receptor-expressing cells in the rat hypothalamus through in vivo agonist stimulation: neuroanatomical evidence for a major role of this subtype in mediating somatostatin functions

scientific article published in April 2003
Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor

scientific article published on 29 September 2009
Hippocampal SSTR4 somatostatin receptors control the selection of memory strategies

scientific article
New Insights in Anorexia Nervosa

scientific article
Caloric restriction increases lifespan but affects brain integrity in grey mouse lemur primates

scientific article published on 05 April 2018
Genetic deletion of somatostatin receptor 1 alters somatostatinergic transmission in the mouse retina

scientific article published in December 2003
The somatostatin sst1 receptor: an autoreceptor for somatostatin in brain and retina?

scientific article
A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice

scientific article
Somatostatin receptor type 2 undergoes plastic changes in the human epileptic dentate gyrus

scientific article published in November 2005
Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality

scientific article published on 16 December 2016
Inhibitory control of growth hormone secretion by somatostatin in rat pituitary GC cells: sst(2) but not sst(1) receptors are coupled to inhibition of single-cell intracellular free calcium concentrations

scientific article published in August 2002
Ghrelin-Derived Peptides: A Link between Appetite/Reward, GH Axis, and Psychiatric Disorders?

scientific article
Cooperation between hippocampal somatostatin receptor subtypes 4 and 2: functional relevance in interactive memory systems

scientific article published in June 2010
Ghrelin and obestatin modulate growth hormone-releasing hormone release and synaptic inputs onto growth hormone-releasing hormone neurons.

scientific article
Neuroendocrine Regulation of Growth Hormone Secretion

scientific article
Actions of Agonists and Antagonists of the ghrelin/GHS-R Pathway on GH Secretion, Appetite, and cFos Activity.

scientific article published on 18 March 2013
An Early Reduction in GH Peak Amplitude in Preproghrelin-Deficient Male Mice Has a Minor Impact on Linear Growth

scientific article published on 20 June 2014
Expression, localization, and functional coupling of the somatostatin receptor subtype 2 in a mouse model of oxygen-induced retinopathy

scientific article published on 3 December 2009
Low Serum Insulin-Like Growth Factor-I Predicts Cognitive Decline in Alzheimer's Disease.

scientific article published on 29 March 2016
Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages

scientific article published on 17 January 2018
AMPA-sst2 somatostatin receptor interaction in rat hypothalamus requires activation of NMDA and/or metabotropic glutamate receptors and depends on intracellular calcium

scientific article
Relationships between Personality Traits, Medial Temporal Lobe Atrophy, and White Matter Lesion in Subjects Suffering from Mild Cognitive Impairment.

scientific article
Delayed age-associated decrease in growth hormone pulsatile secretion and increased orexigenic peptide expression in the Lou C/JaLL rat.

scientific article
Aging, but not tau pathology, impacts olfactory performances and somatostatin systems in THY-Tau22 mice.

scientific article published on 31 October 2014
Role of the ghrelin/obestatin balance in the regulation of neuroendocrine circuits controlling body composition and energy homeostasis

scientific article published on 04 September 2009

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